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5 ht2a receptor antagonist  (MedChemExpress)


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    Structured Review

    MedChemExpress 5 ht2a receptor antagonist
    5 Ht2a Receptor Antagonist, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ht2a+antagonist/RS-102221+hydrochloride/pm41448357-101-59-66
    Average 93 stars, based on 3 article reviews
    5 ht2a receptor antagonist - by Bioz Stars, 2026-09
    93/100 stars

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    Article Title: A Drosophila chemical screen reveals synergistic effect of MEK and DGKα inhibition in Ras-driven cancer.
    Article Snippet: Compounds potentially synergistic with trametinib Compound name Source Reported function Concentrations tested AC-93253 iodide Santa Cruz Biotechnology, 108527-83-9 Cell permeable, selective retinoic acid receptor agonist, Src inhibitor 25 μM Carbinoxamine maleate salt MedChemExpress, HY-B1589A Histamine H1 receptor antagonist 25 μM CGP 57380 Cayman Chemical, 13322 Selective inhibitor of MNK1 25 μM, 50 μM GSK 2126458 Selleck Chemicals, S2658 PI3K inhibitor 2.5 μM, 25 μM Guvacine (hydrochloride) Cayman Chemical, 23361 Amino acid found in Areca catechu; inhibits GABA uptake 25 μM, 50 μM Hesperidin MedChemExpress, HY-15337 Bioflavinoid 25 μM JS-K Cayman Chemical, 21225 Nitric oxide donor 25 μM LY294002 MedChemExpress, HY-1010 Broad-spectrum PI3K inhibitor 25 μM Methotrexate MedChemExpress, HY-14519 Folate antagonist 2.5 μM, 5 μM, 25 μM NU7441 Selleck Chemicals, S2638 Potent and selective DNA-PK inhibitor 25 μM, 50 μM Pralatrexate MedChemExpress, HY-10446 Folate antagonist 2.5 μM, 5 μM, 25 μM Propylpyrazole triol Cayman Chemical, 10008841 Estrogen receptor α agonist 25 μM, 50 μM R1487 (hydrochloride) MedChemExpress, HY-14975 Selective inhibitor of p38α 25 μM, 50 μM Ritanserin Santa Cruz Biotechnology, sc-203681 5-HT2A antagonist and DGK inhibitor 25 μM, 50 μM, 100 μM, 250 μM SB 202190 MedChemExpress, HY-10295 Inhibits p38 and p38β2 25 μM SKF81297 Toronto Research Chemicals, S550020 A selective agonist of the dopamine D1-like receptor 25 μM, 50 μM Temsirolimus Cayman Chemical, 11590 mTOR inhibitor 2.5 μM, 5 μM, 10 μM, 20 μM, 25 μM Trametinib MedChemExpress, HY-10999 MEK inhibitor 1.25 μM, 2.5 μM, 5 μM Volasertib MedChemExpress, HY-12137 PLK1 inhibitor 2.5 μM, 5 μM, 12.5 μM, 25 μM XL413 (hydrochloride) MedChemExpress, HY-15260A Potent, selective and ATP-competitive inhibitor of Cdc7; also shows potency on CK2 and PIM1 25 μM This table lists compounds identified in the primary screen that were potentially synergistic with trametinib at reducing scrib−/RasV12 tumour size.



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